Formulation and evaluation of in-situ gels enriched with Tropicamide loaded solid lipid nanoparticles
نویسندگان
چکیده
منابع مشابه
Formulation & Evaluation of Gemcitabine Hydrochloride Loaded Solid Lipid Nanoparticles
INTRODUCTION Gemcitabine hydrochloride is an antimetabolite (pyrimidine analog) with poor oral bioavailability (9%) due to the first pass metabolism. GEM is a water soluble drug (log p = -1.4) with a short half-life of 42 to 94 minutes (short infusions) and 245 to 638 minutes (long infusions) respectively. Extensive first pass metabolism, low bioavailability, high dosing frequency and less half...
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ژورنال
عنوان ژورنال: International Journal of Research in Pharmaceutical Sciences
سال: 2018
ISSN: 0975-7538
DOI: 10.26452/ijrps.v9i1.1250